Experimental Evaluation of Host Adaptation of Lactobacillus reuteri to Different Vertebrate Species.

ABSTRACT: The species Lactobacillus reuteri has diversified into host-specific lineages, implying a long-term association with different vertebrates. Strains from rodent lineages show specific adaptations to mice, but the processes underlying the evolution of L. reuteri in other hosts remain unknown. We administered three standardized inocula composed of strains from different host-confined lineages to mice, pigs, chickens, and humans. The ecological performance of each strain in the gastrointestinal tract of each host was determined by typing random colonies recovered from fecal samples collected over five consecutive days postadministration. Results revealed that rodent strains were predominant in mice, confirming previous findings of host adaptation. In chickens, poultry strains of

SUBMITTER: Duar RM 

PROVIDER: S-EPMC5452824 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature