Effect of Antimicrobial and Physical Treatments on Growth of Multispecies Staphylococcal Biofilms.

ABSTRACT: The prevalence and structure of Staphylococcus aureus and Staphylococcus epidermidis within multispecies biofilms were found to depend sensitively on physical environment and antibiotic dosage. Although these species commonly infect similar sites, such as orthopedic implants, little is known about their behavior in multispecies communities, particularly in response to treatment. This research establishes that S. aureus is much more prevalent than S. epidermidis when simultaneously seeded and grown under unstressed conditions (pH 7, 37°C) in both laboratory and clinical strains. In multispecies communities, S. epidermidis is capable of growing a more confluent biofilm when the addition of S. aureus is delayed 4 to 6 h during 18 h of growth. Different vancomycin dosages generate various beha

SUBMITTER: Stewart EJ 

PROVIDER: S-EPMC5452825 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature