Modeling Deficits From Early Auditory Information Processing to Psychosocial Functioning in Schizophrenia.

ABSTRACT:

Importance

Neurophysiologic measures of early auditory information processing (EAP) are used as endophenotypes in genomic studies and biomarkers in clinical intervention studies. Research in schizophrenia has established correlations among measures of EAP, cognition, clinical symptoms, and functional outcome. Clarifying these associations by determining the pathways through which deficits in EAP affect functioning would suggest when and where to therapeutically intervene.

Objectives

To characterize the pathways from EAP to outcome and to estimate the extent to which enhancement of basic information processing might improve cognition and psychosocial functioning in schizophrenia.

Design, setting, and participants

Cross-sectional data were analyzed using structural equa

SUBMITTER: Thomas ML 

PROVIDER: S-EPMC5453308 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature