Role of metastasis-associated protein 1 in prognosis of patients with digestive tract cancers: A meta-analysis.

ABSTRACT:

Objectives

Metastasis-associated protein 1 (MTA1) is a transcriptional regulator and significantly associated with prognosis of patients with cancer. However, its role as a potential prognostic marker in digestive tract cancer (DTC) is controversial. In this study, a meta-analysis was conducted to evaluate the MTA1 expression as a predictor of clinicopathology and survival of patients with DTC.

Methods

We searched PubMed, Ovid, Web of Science and Cochrane databases using multiple search strategies for eligible studies. STATA 11.0 software was used to pool the data and analyze the association, odds ratios (ORs) and 95% confidence intervals (CIs) were used to measure the strength of the association. Furthermore, the Newcastle-Ottawa scale was used to evaluate the quality of el

SUBMITTER: Cao GD 

PROVIDER: S-EPMC5453427 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature