Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress.

ABSTRACT: Lactobacillus acetotolerans is a major microbe contributing to the Chinese liquor fermentation with unknown function. It can be grown well in a high concentration of ethanol. RNA sequencing (RNA-seq) was performed on L. acetotolerans F28 growing in 12% ethanol to determine important genetic mechanisms for both a short and long term adaption to this environment. A genome-wide transcriptional analysis revealed that the most important genetic elements for L. acetotolerans F28 grown in ethanol are related to high levels of stress response and fatty acid biosynthesis, and a reduction of amino acid transport and metabolism after both a short and long time stress. The fatty acid methyl ester analyses showed that most fatty acids were increased in L. acetotolerans F28 after exposure to ethanol whi

SUBMITTER: Yang X 

PROVIDER: S-EPMC5453994 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature