Independent and cumulative effects of resting heart rate and pulse pressure with type 2 diabetes mellitus in Chinese rural population.

ABSTRACT: The purpose was to explore the effects of resting heart rate (RHR) and pulse pressure (PP) independently as well as their cumulative effects on the risk of type 2 diabetes mellitus (T2DM) through cross-sectional study plus meta-analysis. A total of 8276 subjects aged 35-74 years from the Rural Diabetes, Obesity and Lifestyle (RuralDiab) study were included in the study. Meanwhile, two meta-analyses were conducted to validate the results of the epidemiological research. The results showed that RHR and PP were associated with higher risk of T2DM, and the corresponding adjusted OR(95%CI) for each quartiles were 1.00, 0.99(0.68-1.42), 1.58(1.13-2.20), 2.93(2.15-3.98) and 1.00, 1.06(0.75-1.48), 1.11(0.79-1.56), 1.45(1.03-2.03), respectively. The cumulative effect analysis indicated that the adj

SUBMITTER: Wang P 

PROVIDER: S-EPMC5454018 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature