Ontology highlight
ABSTRACT:
SUBMITTER: Wang XR
PROVIDER: S-EPMC5454262 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Wang Xin Rui XR Ling Li Bin LB Huang Hsiao Han HH Lin Jau Jyun JJ Fugmann Sebastian D SD Yang Shu Yuan SY
Proceedings. Biological sciences 20170501 1855
<i>PHD finger protein 7</i> (<i>Phf7</i>) is a male germline specific gene in <i>Drosophila melanogaster</i> that can trigger the male germline sexual fate and regulate spermatogenesis, and its human homologue can rescue fecundity defects in male flies lacking this gene. These findings prompted us to investigate conservation of reproductive strategies through studying the evolutionary origin of this gene. We find that <i>Phf7</i> is present only in select species including mammals and some insec ...[more]