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Association of the Asp1312Gly Thyroglobulin Gene Polymorphism with Susceptibility to Differentiated Thyroid Cancer in an Iranian Population


ABSTRACT: Background and aim: While the causes of thyroid cancer in most patients remain largely unknown, it has recently

SUBMITTER: Abidi M 

PROVIDER: S-EPMC5454750 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Association of the Asp1312Gly Thyroglobulin Gene Polymorphism with Susceptibility to Differentiated Thyroid Cancer in an Iranian Population

Abidi Maryam M   Fayaz Shima Sh   Fard Esfahani Pezhman P  

Asian Pacific journal of cancer prevention : APJCP 20170201 2


Background and aim: While the causes of thyroid cancer in most patients remain largely unknown, it has recently been reported that there may be links to particular chromosome regions. In particular, polymorphisms (SNPs) in the thyroglobulin (TG) gene could be susceptibility factors. Methods: In this case-control study, any association of the Asp1312Gly single nucleotide polymorphism (SNP) in the TG gene (rs2069556) with susceptibility to differentiated thyroid cancer (DTC) was investigated among  ...[more]

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