Trials directly comparing alternative spontaneous breathing trial techniques: a systematic review and meta-analysis.

ABSTRACT:

Background

The effect of alternative spontaneous breathing trial (SBT) techniques on extubation success and other clinically important outcomes is uncertain.

Methods

We searched MEDLINE, EMBASE, CENTRAL, CINAHL, Evidence-Based Medicine Reviews, Ovid Health Star, proceedings of five conferences (1990-2016), and reference lists for randomized trials comparing SBT techniques in intubated adults or children. Primary outcomes were initial SBT success, extubation success, or reintubation. Two reviewers independently screened citations, assessed trial quality, and abstracted data.

Results

We identified 31 trials (n = 3541 patients). Moderate-quality evidence showed that patients undergoing pressure support (PS) compared with T-piece SBTs (nine trials, n = 1901) were as likel

SUBMITTER: Burns KEA 

PROVIDER: S-EPMC5455092 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature