An Intriguing Method for Fabricating Arbitrarily Shaped "Matreshka" Hydrogels Using a Self-Healing Template.

ABSTRACT: This work describes an intriguing strategy for the creation of arbitrarily shaped hydrogels utilizing a self-healing template (SHT). A SHT was loaded with a photo-crosslinkable monomer, PEG diacrylate (PEGDA), and then ultraviolet light (UV) crosslinked after first shaping. The SHT template was removed by simple washing with water, leaving behind the hydrogel in the desired physical shape. A hierarchical 3D structure such as "Matreshka" boxes were successfully prepared by simply repeating the "self-healing" and "photo-irradiation" processes. We have also explored the potential of the SHT system for the manipulation of cells.

SUBMITTER: Sato T 

PROVIDER: S-EPMC5457250 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature