Differential Use of Screening Mammography in Older Women Initiating Metformin versus Sulfonylurea.

ABSTRACT:

Purpose

Differential use of screening mammography may lead to biased detection of breast cancer. This study aimed to compare receipt of screening mammography and the incidence of screen-detected breast cancer between metformin and sulfonylurea initiators.

Methods

We used 2006-2014 US Medicare claims to identify initiators of metformin or sulfonylurea aged 65+ years continuously enrolled in Parts A/B for ≥2 years pre-initiation and ≥2 years post-initiation. We reported frequencies of screening mammograms and screen-detected breast cancer in 1 year pre-initiation among all cohort members and in 1 year post-initiation among cancer-free cohort members. Weighted screening risk differences (RDs) were estimated comparing metformin to sulfonylurea group.

Results

We identified

SUBMITTER: Hong JL 

PROVIDER: S-EPMC5457352 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature