Artificial enamel induced by phase transformation of amorphous nanoparticles.

ABSTRACT: Human tooth enamel has tightly packed c-axis-oriented hydroxyapatite (HAP: Ca₁₀(PO₄)₆(OH)₂) nanorods with high elastic modulus. Fabrication of an enamel architecture in vitro supports the repair of teeth using HAP; however, existing methods require complex and laborious steps to form an enamel-like structure. Here we present a very simple and effective technique for forming artificial enamel in near-physiological solution using a substrate composed of amorphous calcium phosphate (ACP) nanoparticles. Without any functionalized modification of the substrate surface, faint dissolution and successive phase transformation automatically induce formation of an intermediate layer of low-crystalline HAP nanoparticles, on which highly oriented HAP nanorods

SUBMITTER: Onuma K 

PROVIDER: S-EPMC5457434 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature