Finding the Genomic Basis of Local Adaptation: Pitfalls, Practical Solutions, and Future Directions.

ABSTRACT: Uncovering the genetic and evolutionary basis of local adaptation is a major focus of evolutionary biology. The recent development of cost-effective methods for obtaining high-quality genome-scale data makes it possible to identify some of the loci responsible for adaptive differences among populations. Two basic approaches for identifying putatively locally adaptive loci have been developed and are broadly used: one that identifies loci with unusually high genetic differentiation among populations (differentiation outlier methods) and one that searches for correlations between local population allele frequencies and local environments (genetic-environment association methods). Here, we review the promises and challenges of these genome scan methods, including correcting for the confoundin

SUBMITTER: Hoban S 

PROVIDER: S-EPMC5457800 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature