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Computing Substrate Selectivity in a Peptide Transporter.


ABSTRACT: The human proton-coupled peptide transporter 1 (PepT1) is responsible for the absorption of di- and tri-peptides from the diet and peptide-like drugs. In this issue of Cell Chemical Biology, Samsudin et al. (2016) use an integrated computational and experimental approach to provide new insights into understanding substrate selectivity of PepTSt, a prokaryotic homolog of the human PepT1.

SUBMITTER: Colas C 

PROVIDER: S-EPMC5457801 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature