Accuracy, precision, and reproducibility of myocardial T1 mapping: A comparison of four T1 estimation algorithms for modified look-locker inversion recovery (MOLLI).

ABSTRACT:

Purpose

To compare the accuracy and precision of four different T1 estimation algorithms for modified Look-Locker inversion recovery (MOLLI).

Methods

Four T1 estimation algorithms, including the original fit, inversion group (IG) fit, instantaneous signal loss simulation (InSiL), and Bloch equation simulation with slice profile correction (BLESSPC) were studied. T1 estimation accuracy, precision, reproducibility, and sensitivity to heart rate (HR), flip angle (FA), and acquisition scheme (AcS) variations were compared in simulation, phantom, and volunteer studies.

Results

T1 estimation accuracy of IG (-2.4% ± 3.9%) and original fit (-3.2% ± 1.4%) were worse than BLESSPC (0.2% ± 1.5%) and InSiL (-0.7% ± 2.1%). The original fit had the best precision for T1 from 409-188

SUBMITTER: Shao J 

PROVIDER: S-EPMC5457913 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature