Ontology highlight
ABSTRACT:
SUBMITTER: Tsoi LC
PROVIDER: S-EPMC5458077 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Nature communications 20170524
Psoriasis is a complex disease of skin with a prevalence of about 2%. We conducted the largest meta-analysis of genome-wide association studies (GWAS) for psoriasis to date, including data from eight different Caucasian cohorts, with a combined effective sample size >39,000 individuals. We identified 16 additional psoriasis susceptibility loci achieving genome-wide significance, increasing the number of identified loci to 63 for European-origin individuals. Functional analysis highlighted the ro ...[more]