Control of Selectivity through Synergy between Catalysts, Silanes and Reaction Conditions in Cobalt-Catalyzed Hydrosilylation of Dienes and Terminal Alkenes.

ABSTRACT: Readily accessible ( ^i-PrPDI)CoCl₂ [ ^i-Pr PDI = 2,6-bis(2,6-diisopropylphenyliminoethyl)pyridine] reacts with 2 equivalents of NaEt₃BH at -78 °C in toluene to generate a catalyst that effects highly selective anti-Markovnikov hydrosilylation of the terminal double bond in 1,3- and 1,4-dienes. Primary and secondary silanes such as PhSiH₃, Ph₂SiH₂ and PhSi(Me)H₂ react with a broad spectrum of terminal dienes without affecting the configuration of the other double bond. When dienes conjugated to an aromatic ring are involved, both Markovnikov and anti-Markovnikov products are formed. The reaction is tolerant of various functional groups such as an aryl bromide, ar

SUBMITTER: Raya B 

PROVIDER: S-EPMC5459319 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature