Acetic Acid Promoted Redox Annulations with Dual C-H Functionalization.

ABSTRACT: Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with 2-alkylquinoline-3-carbaldehydes as well as the corresponding 4-alkyl isomers and pyridine analogues. These processes involve dual C-H bond functionalization. Acetic acid is used as a cosolvent and acts as the sole promoter of these transformations.

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC5460294 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature