The skeletal proteome of the sea star Patiria miniata and evolution of biomineralization in echinoderms.

ABSTRACT:

Background

Proteomic studies of skeletal proteins have revealed large, complex mixtures of proteins occluded within the mineral. Many skeletal proteomes contain rapidly evolving proteins with repetitive domains, further complicating our understanding. In echinoderms, proteomic analysis of the skeletal proteomes of mineralized tissues of the sea urchin Strongylocentrotus purpuratus prominently featured spicule matrix proteins with repetitive sequences linked to a C-type lectin domain. A comparative study of the brittle star Ophiocoma wendtii skeletal proteome revealed an order of magnitude fewer proteins containing C-type lectin domains. A number of other proteins conserved in the skeletons of the two groups were identified. Here we report the complete skeletal proteome of the sea s

SUBMITTER: Flores RL 

PROVIDER: S-EPMC5460417 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature