Prevalence and distribution of Gardnerella vaginalis subgroups in women with and without bacterial vaginosis.

ABSTRACT:

Background

Bacterial vaginosis (BV) is one of the leading causes of vaginal complaints among women of childbearing age. The role of Gardnerella vaginalis remains controversial due to its presence in healthy and BV-type vaginal microflora. The phenotypic and genotypic heterogeneity of G. vaginalis suggested the existence of strain variants linked with different health conditions. We sought to analyze prevalence and distribution of G. vaginalis subgroups (clades) in BV-positive (n = 29), partial BV (n = 27), and BV-negative (n = 53) vaginal samples from Lithuanian women.

Methods

Vaginal samples were characterized by Amsel criteria and the Nugent method. Bacterial signatures characteristic of BV and concomitant infections were identified by culture and PCR. Using singleplex PCR

SUBMITTER: Janulaitiene M 

PROVIDER: S-EPMC5460423 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature