Albuminuria, Proteinuria, and Renal Disease Progression in Children with CKD.

ABSTRACT:

Background and objectives

The role of albuminuria as an indicator of progression has not been investigated in children with CKD in the absence of diabetes.

Design, setting, participants, & measurements

Children were enrolled from 49 centers of the CKD in Children study between January of 2005 and March of 2014. Cross-sectional multivariable linear regression (n=647) was used to examine the relationship between urine protein-to-creatinine (UP/C [milligrams per milligram]) and albumin-to-creatinine (ACR [milligrams per gram]) with eGFR (milliliters per minute per 1.73 m²). Parametric time-to-event analysis (n=751) was used to assess the association of UP/C, ACR, and urine nonalbumin-to-creatinine (Unon-alb/cr [milligrams per gram]) on the time to the c

SUBMITTER: Fuhrman DY 

PROVIDER: S-EPMC5460717 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature