Examining the Association between Hemodialysis Access Type and Mortality: The Role of Access Complications.

ABSTRACT: BACKGROUND AND OBJECTIVES:People receiving hemodialysis to treat kidney failure need a vascular access (a fistula, a graft, or a central venous catheter) to connect to the blood purification machine. Higher rates of access complications are considered the mechanism responsible for the excess mortality observed among catheter or graft users versus fistula users. We tested this hypothesis using mediation analysis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS:We studied incident patients who started hemodialysis therapy from North America, Europe, and Australasia (the Dialysis Outcomes and Practice Patterns Study; 1996-2011). We evaluated the association between access type and time to noninfectious (e.g., thrombosis) and infectious complications of the access (mediator model) and the relati

SUBMITTER: Ravani P 

PROVIDER: S-EPMC5460718 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature