Thyroid hormones and changes in body weight and metabolic parameters in response to weight loss diets: the POUNDS LOST trial.

ABSTRACT:

Background

The role of thyroid hormones in diet-induced weight loss and subsequent weight regain is largely unknown.

Objectives

To examine the associations between thyroid hormones and changes in body weight and resting metabolic rate (RMR) in a diet-induced weight loss setting.

Subjects/methods

Data analysis was conducted among 569 overweight and obese participants aged 30-70 years with normal thyroid function participating in the 2-year Prevention of Obesity Using Novel Dietary Strategies (POUNDS) LOST randomized clinical trial. Changes in body weight and RMR were assessed during the 2-year intervention. Thyroid hormones (free triiodothyronine (T3), free thyroxine (T4), total T3, total T4 and thyroid-stimulating hormone (TSH)), anthropometric measurements and bioche

SUBMITTER: Liu G 

PROVIDER: S-EPMC5461198 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature