NaviSE: superenhancer navigator integrating epigenomics signal algebra.

ABSTRACT:

Background

Superenhancers are crucial structural genomic elements determining cell fate, and they are also involved in the determination of several diseases, such as cancer or neurodegeneration. Although there are pipelines which use independent pieces of software to predict the presence of superenhancers from genome-wide chromatin marks or DNA-interaction protein binding sites, there is not yet an integrated software tool that processes automatically algebra combinations of raw data sequencing into a comprehensive final annotated report of predicted superenhancers.

Results

We have developed NaviSE, a user-friendly streamlined tool which performs a fully-automated parallel processing of genome-wide epigenomics data from sequencing files into a final report, built with a comp

SUBMITTER: Ascension AM 

PROVIDER: S-EPMC5461685 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature