Genome-wide scans for the identification of Plasmodium vivax genes under positive selection.

ABSTRACT:

Background

The current trend of Plasmodium vivax cases imported from Southeast Asia into China has sharply increased recently, especially from the China-Myanmar border (CMB) area. High recombination rates of P. vivax populations associated with varied transmission intensity might cause distinct local selective pressures. The information on the genetic variability of P. vivax in this area is scant. Hence, this study assessed the genetic diversity of P. vivax genome sequence in CMB area and aimed to provide information on the positive selection of new gene loci.

Results

This study reports a genome-wide survey of P. vivax in CMB area, using blood samples from local patients to identify population-specific selective processes. The result showed that considerable genetic diversit

SUBMITTER: Shen HM 

PROVIDER: S-EPMC5461743 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature