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DNA-Targeted Precision Medicine; Have we Been Caught Sleeping?

ABSTRACT: In the current drive to incorporate molecular markers into treatment-selection for precision medicine, there has been a significant and we believe ill-advised omission of the large and routinely used group of drugs whose mechanism of action is DNA damage.

SUBMITTER: Reinhold WC 

PROVIDER: S-EPMC5461960 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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DNA-Targeted Precision Medicine; Have we Been Caught Sleeping?

Reinhold William C WC   Thomas Anish A   Pommier Yves Y  

Trends in cancer 20170101 1

In the current drive to incorporate molecular markers into treatment-selection for precision medicine, there has been a significant and we believe ill-advised omission of the large and routinely used group of drugs whose mechanism of action is DNA damage. ...[more]

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