Genetic variation of dopamine and serotonin function modulates the feedback-related negativity during altruistic punishment.

ABSTRACT: Why do humans cooperate and often punish norm violations of others? In the present study, we sought to investigate the genetic bases of altruistic punishment (AP), which refers to the costly punishment of norm violations with potential benefit for other individuals. Recent evidence suggests that norm violations and unfairness are indexed by the feedback-related negativity (FRN), an anterior cingulate cortex (ACC) generated neural response to expectancy violations. Given evidence on the role of serotonin and dopamine in AP as well as in FRN-generation, we explored the impact of genetic variation of serotonin and dopamine function on FRN and AP behavior in response to unfair vs. fair monetary offers in a Dictator Game (DG) with punishment option. In a sample of 45 healthy participants we obs

SUBMITTER: Enge S 

PROVIDER: S-EPMC5462809 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature