Mortality risk in patients with chronic rhinosinusitis and its association to asthma.

ABSTRACT:

Background

Chronic rhinosinusitis (CRS) is a highly prevalent inflammatory condition, with significant effects on morbidity and quality of life. Given that other chronic inflammatory conditions have been associated with increased mortality risk, we sought to evaluate the relationship between mortality and CRS including the influence of asthma. Our objective was to determine if CRS, with or without asthma, is associated with altered risk of mortality.

Methods

Using a statewide population database, we retrospectively identified 27,005 patients diagnosed with CRS between 1996 and 2012, and 134,440 unaffected controls matched 5:1 on birth year and sex. Risk of mortality was determined from Cox models and Kaplan-Meier curves were used to compare survival.

Results

A signifi

SUBMITTER: Alt JA 

PROVIDER: S-EPMC5462840 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature