New Frontiers in the Pathobiology and Treatment of Cancer Regimen-Related Mucosal Injury.

ABSTRACT: Mucositis is a common complication of chemotherapy, radiotherapy and targeted agents. It often affects compliance to anticancer therapies as it frequently causes schedule delays, interruptions or discontinuations of treatment. Moreover, the economic impact related to the management of mucositis is topical and several estimations of additional hospital costs due to this clinical condition have been recently reported. The ability to determine risk factors for mucositis, to early detect its onset, to assess correctly the degree of this toxicity and to plan its multidisciplinary management are all key elements to guarantee the quality of life of patients and to avoid useless dose reduction or interruption of treatment. The pathogenesis of mucositis is multifactorial and it is classily subdivid

SUBMITTER: Cinausero M 

PROVIDER: S-EPMC5462992 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature