Cancers of the brain and CNS: global patterns and trends in incidence.

ABSTRACT:

Background

Cancers of the brain and CNS constitute a group of rare and heterogeneous tumors. Increasing incidence in Western populations has been linked to improvements in diagnostic technology, although interpretation is hampered by changes in diagnosis and reporting. The present study examines geographic and temporal variations in incidence rates of brain and CNS cancers worldwide.

Methods

Data from successive volumes of Cancer Incidence in Five Continents were used, including 96 registries in 39 countries. We used Joinpoint regression to estimate the average annual percentage change and its 95% CI.

Results

Globally, a large variability in the magnitude of the diagnosis of new cases of brain and CNS cancer was found, with a 5-fold difference between the highest rate

SUBMITTER: Miranda-Filho A 

PROVIDER: S-EPMC5464292 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature