Ontology highlight
ABSTRACT:
SUBMITTER: Yang CF
PROVIDER: S-EPMC5464665 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Yang Ching-Fen CF Ho Hsiang-Ling HL Lin Shih-Chieh SC Hsu Chih-Yi CY Ho Donald Ming-Tak DM
PloS one 20170608 6
The relationship between human cytomegalovirus (HCMV) and glioblastoma (GBM) has been debated for more than a decade. We investigated the presence of HCMV genes, RNA and protein in GBMs and their relationships with tumor progression. Results of quantitative PCR for HCMV UL73, nested PCR for HCMV UL144, in situ hybridization (ISH) for RNA transcript, and immunohistochemistry (IHC) for protein expression and their relationship to the prognosis of 116 patients with GBM were evaluated. Nine (7.8%) c ...[more]