High-Throughput Analysis of in-vitro LFP Electrophysiological Signals: A validated workflow/software package.

ABSTRACT: Synchronized brain activity in the form of alternating epochs of massive persistent network activity and periods of generalized neural silence, has been extensively studied as a fundamental form of circuit dynamics, important for many cognitive functions including short-term memory, memory consolidation, or attentional modulation. A key element in such studies is the accurate determination of the timing and duration of those network events. The local field potential (LFP) is a particularly attractive method for recording network activity, because it allows for long and stable recordings from multiple sites, allowing researchers to estimate the functional connectivity of local networks. Here, we present a computational method for the automatic detection and quantification of in-vitro LFP ev

SUBMITTER: Tsakanikas P 

PROVIDER: S-EPMC5465098 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature