Effects of Dietary Nitrate Supplementation on Physiological Responses, Cognitive Function, and Exercise Performance at Moderate and Very-High Simulated Altitude.

ABSTRACT: Purpose: Nitric oxide (NO) bioavailability is reduced during acute altitude exposure, contributing toward the decline in physiological and cognitive function in this environment. This study evaluated the effects of nitrate ([Formula: see text]) supplementation on NO bioavailability, physiological and cognitive function, and exercise performance at moderate and very-high simulated altitude. Methods:Ten males (mean (SD): [Formula: see text]: 60.9 (10.1) ml·kg^-1·min^-1) rested and performed exercise twice at moderate (~14.0% O₂; ~3,000 m) and twice at very-high (~11.7% O₂; ~4,300 m) simulated altitude. Participants ingested either 140 ml concentrated [Formula: see text]-rich (BRJ; ~12.5 mmol [Formula: see text]) or [Formula: see text]-d

SUBMITTER: Shannon OM 

PROVIDER: S-EPMC5465306 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature