Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC5465934 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Wang Hanbo H Yin Xuefeng X Wu Orr Mona M Dambach Michael M Curtis Rebecca R Storz Gisela G
Proceedings of the National Academy of Sciences of the United States of America 20170516 22
Synthesis of the 31-amino acid, inner membrane protein MgtS (formerly denoted YneM) is induced by very low Mg<sup>2+</sup> in a PhoPQ-dependent manner in <i>Escherichia coli</i> Here we report that MgtS acts to increase intracellular Mg<sup>2+</sup> levels and maintain cell integrity upon Mg<sup>2+</sup> depletion. Upon development of a functional tagged derivative of MgtS, we found that MgtS interacts with MgtA to increase the levels of this P-type ATPase Mg<sup>2+</sup> transporter under Mg<su ...[more]