Patient Survey of current water Intake practices in autosomal dominant Polycystic kidney disease: the SIPs survey.

ABSTRACT: Background: Autosomal dominant polycystic kidney disease (ADPKD) affects 12.5 million worldwide. Vasopressin drives cysts growth and in animal models can be suppressed through high water intake. A randomized controlled trial of 'high' versus 'standard' water intake in ADPKD is essential to determine if this intervention is beneficial. We conducted an ADPKD patient survey to gain an understanding of current fluid intake practices and the design challenges of a randomized water intake trial. Methods: In collaboration with the PKD Charity, we developed and distributed an online survey to ADPKD patients over age 16 years and not on renal replacement therapy. Results: Of the 2377 invited, 89 ADPKD patients completed the Survey of current water Intake practices in autosomal

SUBMITTER: El-Damanawi R 

PROVIDER: S-EPMC5466085 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature