Association of Optimal Combination Drug Treatment with Obesity Status among Recent Ischemic Stroke Patients: Results of the Vitamin Intervention for Stroke Prevention (VISP) Trial.

ABSTRACT:

Background and purpose

One explanation for the 'obesity paradox', where obese patients seem to have better cardiovascular outcomes than lean patients, is that obese patients display an identifiable high cardiovascular risk phenotype that may lead to receiving or seeking earlier/more aggressive treatment.

Methods

We analyzed a clinical trial dataset comprising 3643 recent (<120 days) ischemic stroke patients followed up for 2 years. Subjects were categorized as lean (body mass index [BMI], <25 kg/m², n=1,006), overweight (25-29.9 kg/m², n=1,493), or obese (≥30 kg/m², n=1,144). Subjects were classified as level 0 to III depending on the number of secondary prevention prescriptions divided by the number of potentially indicated drugs (0=none of

SUBMITTER: Park JH 

PROVIDER: S-EPMC5466287 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature