Diagnostic value and relative weight of sequence-specific magnetic resonance features in characterizing clinically significant prostate cancers.

ABSTRACT:

Purpose

To assess the diagnostic weight of sequence-specific magnetic resonance features in characterizing clinically significant prostate cancers (csPCa).

Materials and methods

We used a prospective database of 262 patients who underwent T2-weighted, diffusion-weighted, and dynamic contrast-enhanced (DCE) imaging before prostatectomy. For each lesion, two independent readers (R1, R2) prospectively defined nine features: shape, volume (V_Max), signal abnormality on each pulse sequence, number of pulse sequences with a marked (S_Max) and non-visible (S_Min) abnormality, likelihood of extracapsular extension (ECE) and PSA density (dPSA). Overall likelihood of malignancy was assessed using a 5-level Likert score. Features were evaluated using the area under the receiver operati

SUBMITTER: Rouviere O 

PROVIDER: S-EPMC5466299 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature