Neurological failure in ICU patients with hematological malignancies: A prospective cohort study.

ABSTRACT:

Background

Epidemiological studies of neurological complications in patients with hematological malignancies are scant. The objective of the study was to identify determinants of survival in patients with hematological malignancy and neurological failure.

Methods

Post hoc analysis of a prospective study of adults with hematological malignancies admitted for any reason to one of 17 university or university-affiliated participating ICUs in France and Belgium (2010-2012). The primary outcome was vital status at hospital discharge.

Results

Of the 1011 patients enrolled initially, 226 (22.4%) had neurological failure. Presenting manifestations were dominated by drowsiness or stupor (65%), coma (32%), weakness (26%), and seizures (19%). Neuroimaging, lumbar puncture, and el

SUBMITTER: Marzorati C 

PROVIDER: S-EPMC5466302 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature