Familial Aggregation of Migraine and Depression: Insights From a Large Australian Twin Sample.

ABSTRACT:

Objectives

This research examined the familial aggregation of migraine, depression, and their co-occurrence.

Methods

Diagnoses of migraine and depression were determined in a sample of 5,319 Australian twins. Migraine was diagnosed by either self-report, the ID migraine™ Screener, or International Headache Society (IHS) criteria. Depression was defined by fulfilling either major depressive disorder (MDD) or minor depressive disorder (MiDD) based on the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria. The relative risks (RR) for migraine and depression were estimated in co-twins of twin probands reporting migraine or depression to evaluate their familial aggregation and co-occurrence.

Results

An increased RR of both migraine and depression in co-tw

SUBMITTER: Yang Y 

PROVIDER: S-EPMC5466692 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature