Extracorporeal life support for acute respiratory failure. A systematic review and metaanalysis.

ABSTRACT:

Rationale

Extracorporeal life support (ECLS) for acute respiratory failure has increased as a result of technological advancements and promising results from recent studies as compared with historical trials.

Objectives

Systematically review the effect of ECLS compared with mechanical ventilation on mortality, length of stay, and adverse events in respiratory failure.

Methods

Data sources included were MEDLINE, EMBASE, and CENTRAL (through to October 2013). Any randomized controlled trial (RCT) or observational study comparing ECLS to mechanical ventilation in adults was used. Two authors independently abstracted the data. Our primary outcome was mortality. Secondary outcomes included intensive care unit length of stay, hospital length of stay, and adverse events. A s

SUBMITTER: Munshi L 

PROVIDER: S-EPMC5467087 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature