TMPL: a database of experimental and theoretical transmembrane protein models positioned in the lipid bilayer.

ABSTRACT: Knowing the position of protein structures within the membrane is crucial for fundamental and applied research in the field of molecular biology. Only few web resources propose coordinate files of oriented transmembrane proteins, and these exclude predicted structures, although they represent the largest part of the available models. In this article, we present TMPL (http://www.dsimb.inserm.fr/TMPL/), a database of transmembrane protein structures (α-helical and β-sheet) positioned in the lipid bilayer. It is the first database to include theoretical models of transmembrane protein structures, making it a large repository with more than 11 000 entries. The TMPL database also contains experimentally solved protein structures, which are available as either atomistic or coarse-grained models.

SUBMITTER: Postic G 

PROVIDER: S-EPMC5467549 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature