Ensembl core software resources: storage and programmatic access for DNA sequence and genome annotation.

ABSTRACT: The Ensembl software resources are a stable infrastructure to store, access and manipulate genome assemblies and their functional annotations. The Ensembl 'Core' database and Application Programming Interface (API) was our first major piece of software infrastructure and remains at the centre of all of our genome resources. Since its initial design more than fifteen years ago, the number of publicly available genomic, transcriptomic and proteomic datasets has grown enormously, accelerated by continuous advances in DNA-sequencing technology. Initially intended to provide annotation for the reference human genome, we have extended our framework to support the genomes of all species as well as richer assembly models. Cross-referenced links to other informatics resources facilitate searching o

SUBMITTER: Ruffier M 

PROVIDER: S-EPMC5467575 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature