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Identification of new hmwA alleles from nontypeable Haemophilus influenzae.

ABSTRACT: High-molecular-weight proteins of Haemophilus influenzae mediate attachment to epithelial cells. Previous reports describe several allelic versions of hmwA genes that have different adherence properties. Here we report three new alleles of hmwA (hmwA from strain AAr96, hmwA from strain AAr105, and hmwA from strain G822), demonstrating the high degree of DNA variation of these genes among different strains.

SUBMITTER: Ecevit IZ 

PROVIDER: S-EPMC546938 | biostudies-literature | 2005 Feb

REPOSITORIES: biostudies-literature

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Identification of new hmwA alleles from nontypeable Haemophilus influenzae.

Ecevit I Zafer IZ   McCrea Kirk W KW   Marrs Carl F CF   Gilsdorf Janet R JR  

Infection and immunity 20050201 2

High-molecular-weight proteins of Haemophilus influenzae mediate attachment to epithelial cells. Previous reports describe several allelic versions of hmwA genes that have different adherence properties. Here we report three new alleles of hmwA (hmwA from strain AAr96, hmwA from strain AAr105, and hmwA from strain G822), demonstrating the high degree of DNA variation of these genes among different strains. ...[more]

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