Self-reported racial/ethnic discrimination and bronchodilator response in African American youth with asthma.

ABSTRACT:

Importance

Asthma is a multifactorial disease composed of endotypes with varying risk profiles and outcomes. African Americans experience a high burden of asthma and of psychosocial stress, including racial discrimination. It is unknown which endotypes of asthma are vulnerable to racial/ethnic discrimination.

Objective

We examined the association between self-reported racial/ethnic discrimination and bronchodilator response (BDR) among African American youth with asthma ages 8 to 21 years (n = 576) and whether this association varies with tumor necrosis factor alpha (TNF-α) level.

Materials and methods

Self-reported racial/ethnic discrimination was assessed by a modified Experiences of Discrimination questionnaire as none or any. Using spirometry, BDR was specified as

SUBMITTER: Carlson S 

PROVIDER: S-EPMC5469454 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature