Negative Ion Mode Electrospray Tandem Mass Spectrometry of Hydroxy-Terminated Polydimethylsiloxanes Formed upon in situ Methanolysis.

ABSTRACT: Ethoxy-, methoxy- and hydroxy-terminated polydimethylsiloxanes (PDMS) are formed as the result of the methanolysis of diethoxy-ended PDMS during its infusion in electrospray ionization. The negative ion mode permits only hydroxy-ended products to be detected, and isomeric interference is avoided in single stage and tandem mass spectrometry. The routes for the fragmentation of (ethyl, hydroxy)-, (methyl, hydroxy)- and (hydro, hydroxy)-ended PDMS upon collision activated dissociation (CAD) were explored in the negative ion mode using either formate or acetate anion adduction. Symmetrical (hydro, hydroxy)-ended PDMS decomposed to product ions carrying one of the hydroxy terminations through the abstraction of an acidic hydrogen and depolymerization (expulsion of cyclic neutral species) regard

SUBMITTER: Fouquet T 

PROVIDER: S-EPMC5469726 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature