Canine Leishmaniasis Progression is Associated with Vitamin D Deficiency.

ABSTRACT: The relationship between vitamin D deficiency and the risk of suffering from a plethora of health disorders, ranging from autoimmune processes to infectious diseases has been widely described. Nonetheless, the potential role of vitamin D in visceral leishmaniasis remains uncharacterized. In the Mediterranean basin, where the dog is leishmania's main peri-domestic reservoir, control measures against the canine disease have shown beneficial effects on the incidence of human leishmaniasis. In this study, we measured the vitamin D levels in serum samples from a cohort of 68 healthy and disease dogs from a highly endemic area and we have also studied the relationship of these levels with parasitological and immunological parameters. The sick dogs presented significantly lower (P < 0.001) vitami

SUBMITTER: Rodriguez-Cortes A 

PROVIDER: S-EPMC5469782 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature