Catalytic transformation of functionalized carboxylic acids using multifunctional rhenium complexes.

ABSTRACT: Carboxylic acids (CAs) are one of the most ubiquitous and important chemical feedstocks available from biorenewable resources, CO₂, and the petrochemical industry. Unfortunately, chemoselective catalytic transformations of CH _n CO₂H (n = 1-3) groups into other functionalities remain a significant challenge. Herein, we report rhenium^V complexes as extremely effective precatalysts for this purpose. Compared to previously reported heterogeneous and homogeneous catalysts derived from high- or low-valent metals, the present method involves a α-C-H bond functionalization, a hydrogenation, and a hydrogenolysis, which affords functionalized alcohols with a wide substrate scope and high chemoselectivity under relatively mild reaction conditions. The resul

SUBMITTER: Naruto M 

PROVIDER: S-EPMC5469866 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature