Serum levels of environmental pollutants is a risk factor for breast cancer in Inuit: a case control study.

ABSTRACT:

Background

Environmental Persistent Organic Pollutants (POPs) can alter the hormone homeostasis by mimicking, interfering or blocking the function of hormones; moreover POPs are hypothesized to modify the risk of breast cancer. The association between POPs and breast cancer has been widely studied but the conclusions are inconsistent. The present study examined the associations between serum levels of POPs and breast cancer with focus on the highly exposed Greenlandic Inuit population.

Methods

The study design was a case-control study of Inuit women from Greenland. The participants were asked to complete a questionnaire with information on reproductive history and lifestyle and to provide a blood sample. The sampling was carried out in two time periods (2000-2003 and 2011-20

SUBMITTER: Wielsoe M 

PROVIDER: S-EPMC5470290 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature