Evaluation of Optical Coherence Tomography to Detect Elevated Intracranial Pressure in Children.

ABSTRACT:

Importance

Detecting elevated intracranial pressure in children with subacute conditions, such as craniosynostosis or tumor, may enable timely intervention and prevent neurocognitive impairment, but conventional techniques are invasive and often equivocal. Elevated intracranial pressure leads to structural changes in the peripapillary retina. Spectral-domain (SD) optical coherence tomography (OCT) can noninvasively quantify retinal layers to a micron-level resolution.

Objective

To evaluate whether retinal measurements from OCT can serve as an effective surrogate for invasive intracranial pressure measurement.

Design, setting, and participants

This cross-sectional study included patients undergoing procedures at the Children's Hospital of Philadelphia from September 20

SUBMITTER: Swanson JW 

PROVIDER: S-EPMC5470406 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature