MRI With Liver-Specific Contrast for Surveillance of Patients With Cirrhosis at High Risk of Hepatocellular Carcinoma.

ABSTRACT:

Importance

Current recommendations for patients with cirrhosis are to undergo surveillance for hepatocellular carcinoma (HCC) with ultrasonography (US) every 6 months. However, the sensitivity of US screening to detect early-stage HCC is suboptimal. Magnetic resonance imaging (MRI) with liver-specific contrast may detect additional HCCs missed by US in high-risk patients with cirrhosis.

Objective

To compare the HCC detection rate of US and MRI in patients with cirrhosis who are at high risk for HCC.

Design, setting, and participants

A prospective surveillance study of 407 patients with cirrhosis and an estimated annual risk of HCC greater than 5% who underwent 1 to 3 biannual screening examinations with paired US and liver-specific contrast-enhanced MRI at a tertiary

SUBMITTER: Kim SY 

PROVIDER: S-EPMC5470420 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature